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Childhood Trauma has Lasting Effect on Brain Connectivity in Patients with Depression

[Source:  Science Daily]

A study found that childhood trauma is linked to abnormal connectivity in the brain in adults with major depressive disorder (MDD). The paper shows symptom-specific, system-level changes in brain network connectivity in MDD.   The paper, published this week in Proceedings of the National Academy of Sciences (PNAS), is the first data-driven study to show symptom-specific, system-level changes in brain network connectivity in MDD.

“With estimates of approximately 10 percent of all children in the United States having been subjected to child abuse, the significance of child maltreatment on brain development and function is an important consideration,” said Yvette I. Sheline, MD,

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