Here’s How the Body Rushes to the Rescue When a Baby has a Stroke
[Source: Science Daily]
New research from the University of Virginia School of Medicine is shedding light on the development of the brain’s immune defenses — and how those defenses respond to strokes that strike one in 4,000 babies in the first month of life.
The brain’s frontline defenders are immune cells known as microglia. These cells make up 10%-15% of all cells found in the brain. But their origins have been hotly debated. UVA’s Chia-Yi “Alex” Kuan, MD, PhD, has discovered that many were previously white blood cells known as monocytes. During brain development — and in response to infant strokes — the monocytes undergo an amazing conversion into troops to defend the brain.
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