Genes Leave Some Kids Prone to Weakness in Wrist Bones
[Source: Medical News Today]
Pediatric researchers have discovered gene locations affecting bone strength in wrist bones, the most common site for fractures in children. Children who have those genetic variants may be at higher-than-average risk of wrist fractures, and could especially benefit from activities and diets that promote bone strength.
“Other genetic studies have analyzed bone strength in adults and over the whole skeleton, but this study focused on genetic influences specific to childhood, which is when future bone density is established,” said co-study leader Struan F.A. Grant, Ph.D., a genomics expert at The Children’s Hospital of Philadelphia (CHOP). “Furthermore, this research was the first genome-wide study in children to examine bone strength of the wrist, a particularly vulnerable site for fractures.”
Grant and colleagues, including first author Alessandra Chesi, Ph.D., and co-study leader Babette S. Zemel, Ph.D., also from CHOP, published the study online June 3 in Human Molecular Genetics.
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