Could Poor Protein Trafficking be a Factor in Autism?
[Source: Medical News Today]
Newly published research — led by Rockefeller University in New York City, NY — reveals that the protein astrotactin 2 (ASTN2) can traffick receptors away from neurons’ surfaces and prevent them from accumulating there.
Connections between neurons are essential to brain function.
They work because receptors, which sit on the surfaces of cells, are always ready to partner with incoming neurotransmitters from other cells.
The process is dynamic and needs a continual cycle of receptors “on and off” the cell membrane to ensure rapid response to signals. Trafficking proteins help keep the receptors moving.
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